Perfusion Study of Hypervascular Hepatocellular Carcinoma with SPIO

Detection of hypervascular hepatocellular carcinoma: comparison of SPIO-enhanced MRI with dynamic helical CT.

PURPOSE The purpose of this study was to compare the diagnostic performance of superparamagnetic iron oxide (SPIO)-enhanced MRI for the detection of hypervascular hepatocellular carcinoma (HCC) with dynamic helical CT. METHODS SPIO-enhanced MR and dynamic helical CT images obtained from 41 patients with 52 hypervascular HCCs (5-130 mm; mean, 27 mm) were retrospectively analyzed. MRI were obta...

Prognostic Significance of Concurrent Hypovascular and Hypervascular Nodules in Patients with Hepatocellular Carcinoma

BACKGROUND Hypovascular nodules often occur together with hypervascular hepatocellular carcinoma (HCC). However, it remains controversial whether hypovascular nodules associated with hypervascular HCC have any prognostic value. This study evaluated the prognostic impact of hypovascular nodules co-existing with hypervascular HCC as diagnosed by computed tomography during arterial portography (CT...

Evaluation of hepatocellular carcinoma with computed tomography perfusion imaging.

AIM To evaluate the role of computed tomography (CT) perfusion imaging in patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS Seventeen patients (9 men, 8 women) with newly diagnosed HCC, proven by biopsy, were evaluated with 256-slice helical CT. Perfusion parameters of blood flow (BF), blood volume (BV), arterial perfusion (AP), portal perfusion (PP), and hepatic perfusion i...

Hepatocellular Carcinoma in Sheep

Stepwise carcinogenesis of hepatocellular carcinoma in a nodule surrounded by hyperplastic and hypervascular liver tissue.

S tepwise carcinogenesis of hepatocellular carcinoma (HCC) in the cirrhotic liver has been well described pathologically and radiologically. It is accompanied by sequential hemodynamic changes in the nodules. The dysplastic nodule (DN, adenomatous hyperplasia) and early HCC frequently include portal tract structures without arterial neovascularization. In contrast, advanced HCC is characterized...